ABSTRACT
The gene approach to the pathogenesis of male infertility may bring about some strategies for the diagnosis and manage of the condition. Gene knockout technology is the mainstream method currently used in the study of gene function. Screening and identification of testis-specific genes and insights into their features and functions in spermatogenesis are significant for a further understanding of testicular functions and searching for new therapeutic targets for male reproductive disorders. This review focuses on the application of gene knockout technology in the study of spermatogenesis-associated genes.
Subject(s)
Animals , Humans , Male , Gene Knockout Techniques , Infertility, Male , Genetics , Spermatogenesis , GeneticsABSTRACT
<p><b>OBJECTIVE</b>To select the main directions and the objects in breeding the high yield of Panax notoginseng by the correlation and path analysis of main agronomic character of P. notoginseng.</p><p><b>METHOD</b>Samples in fifty-two districts of Yunnan and Guangxi were collected. The height of plant, the diameter of stem, the number, length, width, size of leaf and the weight of each root of those samples were measured.</p><p><b>RESULT</b>The greatest contribution to the weight of each root is the size of leaf.</p><p><b>CONCLUSION</b>The size of leaf should be key to the high yield of cultribution of P. notoginseng and the size of leaf especially the width of leaf should be selected in breeding. At the same time, the height of plant and the diameter of stem should be considered.</p>